In 1983, recombinant t-PA was discovered and in the year 1995, the National Institute of Neurological Disorders and Stroke study determined its use in the treatment of acute ischemic stroke.Evidence of ancient Egyptian medicine and its use to treat certain problems was documented in a number of papyri.Thrombolytics for the treatment of ischemic stroke was first started in the year 1958.The invention of CT scan and angiography in the 20th century is one of the major leaps in the medical field and solved many queries regarding cause, and appropriate treatment of stroke.In 1900, further advancements were made by Broca making further correlations to determine the relationship between anatomy and clinical presentations in stroke. Anatomical territories supplied by different blood vessels in the brain and their importance in the clinical correlation of ischemic stroke was first described by Charles Foix.Rudolf Virchow, a German doctor, pathologist and anthropologist gave an insight to the factors causing thromboembolism called virchow's triad and described it as the cause of vascular occlusion, forming the basis for true understanding of pathophysiology of ischemic stroke.Two anatomists, Matthew and Cruveilher described the lesions in stroke in 1800s.In the 1600s, a doctor named Johann Jacob Wepfer discovered the cause of ischemic stroke when he suggested that apoplexy might be caused by a blockage to those vessels.Apoplexy, from the Greek word meaning "struck down with violence,” first appeared in Hippocratic writings to describe this phenomenon.
0 Comments
Leave a Reply. |